Information For all details about LOVD, see our LOVD flyer! (last updated June 6th, 2013)
By the way, did you already know LOVD 3.0 is out?

List of public LOVD installations

Question If you are looking for a specific gene database, please also check our list of LSDBs.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 13,134,726 variants (2,499,258 unique) in 271,005 individuals in 84 LOVD installations.
http://bipmed.iqm.unicamp.br/ LOVD 3.0-14 20868 genes 10150641 variants
QUESTIONS / SUGGESTIONS: Send us an email! A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 200555 unique
http://databases.lovd.nl/whole_genome/ LOVD 3.0-14 22002 genes 1998175 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 1998135 unique
http://databases.lovd.nl/shared/ LOVD 3.0-14c 22082 genes 294383 variants
LOVD 3.0 shared installation A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,... 38509 unique
http://proteomics.bio21.unimelb.edu.au/lovd/ LOVD 3.0-07 14772 genes 239690 variants
LOVD - Leiden Open Variation Database A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A... 152241 unique
https://ab-openlab.csir.res.in/mitolsdb/ LOVD 2.0-35 37 genes 112662 variants
MitoLSDB MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB... 4660 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-36 127 genes 79950 variants
Leiden Muscular Dystrophy pages ACTA1,ANKRD1,ANO5,B3GNT1,BAG3,BANF1,B... 13369 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-36 240 genes 40627 variants
Mendelian genes ABCC11,ABO,ACTB,ACTG1,ACVR1,ADA,ADAMT... 7417 unique
http://chromium.lovd.nl/LOVD2/colon_cancer/ LOVD 2.0-36 10 genes 29443 variants
Colon cancer gene variant databases APC,CDH1,EPCAM,GALNT12,MLH1,MLH3,MSH2... 4630 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-36 482 genes 27608 variants
X-chromosome gene database ACOT9,ACSL4,ACTRT1,AFF2,AGTR2,AKAP14,... 3802 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 8 genes 26167 variants
LOVD - human mismatch repair genes MLH1,MLH1_priors,MSH2,MSH2_priors,MSH... 26167 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-36 20 genes 22383 variants
Retinal and hearing impairment genetic mutation database CDH23,CEACAM16,CERKL,CHM,CLDN14,CLRN1... 3282 unique
http://chromium.lovd.nl/LOVD2/TSC/ LOVD 2.0-36 2 genes 18668 variants
Tuberous sclerosis database TSC1,TSC2 3630 unique
http://www.genomed.org/lovd2/ LOVD 2.0-35 96 genes 15121 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN... 9320 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-36 3 genes 9774 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 681 unique
http://chromium.lovd.nl/LOVD2/ LOVD 2.0-36 29 genes 8570 variants
LOVD - Leiden Open Variation Database ABCA13,ARG1,ASL,ASS1,ATM,ATP1A2,CACNA... 3134 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-36 5 genes 6519 variants
EAHAD Coagulation Factor Variant Databases F7,F8,F9,GP1BA,VWF 1909 unique
https://mseqdr.org/MITO/ LOVD 3.0-14c 1364 genes 3975 variants
MSeqDR-LSDB Mitochondrial Disease Locus Specific Database AADAT,AARS2,AASS,ABAT,ABCA9,ABCB10,AB... 3711 unique
https://lovd.euro-wabb.org/ LOVD 2.0-30 23 genes 3469 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,ARL6,BBIP1,BBS1,BBS10,BBS12,BBS... 1087 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3377 variants
rb1-lsdb RB1 1741 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-36 19 genes 3221 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FKBP... 1684 unique
http://grenada.lumc.nl/LOVD2/COL4A/ LOVD 2.0-36 4 genes 3072 variants
Collagen, type IV, alpha COL4A3,COL4A4,COL4A5,COL4A6 1737 unique
http://grenada.lumc.nl/LOVD2/eye/ LOVD 2.0-36 16 genes 2869 variants
Eye diseases - LOVD ABCC6,ACBD5,ADAMTS10,ADAMTSL4,BBS1,CD... 731 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-36 7 genes 2809 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,... 562 unique
https://grenada.lumc.nl/LOVD2/shared1/ LOVD 2.0-36 114 genes 2767 variants
LOVD - Leiden Open Variation Database AARS,ACO2,ACP5,AGK,ALG11,ANKH,ASXL1,B... 955 unique
http://grenada.lumc.nl/LOVD2/PKD/ LOVD 2.0-36 2 genes 2245 variants
Autosomal Dominant Polycystic Kidney Disease (ADPKD) PKD1,PKD2 76 unique
http://lovd.bx.psu.edu/ LOVD 2.0-36 37 genes 2185 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CN... 2127 unique
http://www.insight-database.org/ LOVD 3.0-14 9 genes 1914 variants
InSiGHT Database APC,EPCAM,FBXO11,MLH1,MLH3,MSH2,MSH6,... 710 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1742 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,... 1034 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-36 8 genes 1555 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 1026 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-36 10 genes 1543 variants
Ehlers Danlos Syndrome Variant Database ADAMTS2,B4GALT7,CHST14,COL3A1,COL5A1,... 973 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-36 5 genes 1498 variants
LOVD - Leiden Open Variation Database NIPBL,PDS5A,PDS5B,SMC1A,SMC3 357 unique
http://secure.ngrl.org.uk/LOVDv.2.0/ LOVD 2.0-28 5 genes 1404 variants
NGRL, Manchester LOVD CHM,KDM6A,L1CAM,MLL2,UBE3A 540 unique
http://www.ncbi.nlm.nih.gov/lovd/ LOVD 2.0-36 5 genes 1150 variants
LOVD at NCBI ABCC6,DOCK8,FAS,IL2RG,OCRL 693 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-36 9 genes 1127 variants
Parkinson's disease Mutation Database ATXN2,DNAJC13,GBA,LRRK2,PARK2,PARK7,P... 983 unique
http://medgen.ua.ac.be/LOVDv.2.0/ LOVD 2.0-33 2 genes 1106 variants
Multiple Osteochondroma Mutation Database EXT1,EXT2 660 unique
http://dbpex.org/ LOVD 2.0-30 13 genes 1081 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PE... 389 unique
http://chromium.lovd.nl/LOVD2/SDH/ LOVD 2.0-36 6 genes 1054 variants
TCA Cycle Gene Mutation Database FH,SDHA,SDHAF2,SDHB,SDHC,SDHD 569 unique
http://mseqdr.lumc.edu/GEDI/ LOVD 3.0-08 298 genes 1012 variants
The Genetic Eye Disorder (GEDI) Variation Database ABCA4,ABCC6,ABHD12,ADAM9,ADAMTS18,AFG... 981 unique
http://mitodyn.org/ LOVD 2.0-36 2 genes 798 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 408 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-36 1 gene 783 variants
HGD mutation database HGD 189 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-36 1 gene 510 variants
Menkes Disease ATP7A 323 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-36 3 genes 500 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 143 unique
http://chromium.lovd.nl/LOVD2/growth/ LOVD 2.0-36 6 genes 491 variants
LOVD - Leiden Open Variation Database GHR,IGF1,IGF1R,IGF2,IGFALS,STAT5B 150 unique
http://www.dbagenes.unito.it/ LOVD 2.0-36 13 genes 397 variants
Diamond-Blackfan Anemia GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,... 254 unique
https://grenada.lumc.nl/LOVD2/UCL-Heart/ LOVD 2.0-36 4 genes 394 variants
FH UCL BHF FTH1,HAMP,LDLR,TFR2 358 unique
http://www-huge.uni-regensburg.de/BEST1_database/ LOVD 2.0-23 1 gene 394 variants
Bestrophin 1 (BEST1) BEST1 269 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-36 5 genes 360 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 283 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-36 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 2 genes 299 variants
Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified using a quantit BRCA1,BRCA2 299 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-36 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://www.icp.ucl.ac.be/vikkula/VAdb/ LOVD 2.0-36 16 genes 248 variants
Vascular Anomaly and Lymphedema Mutation Database CCBE1,CCM2,FLT4,FOXC2,GATA2,GJC2,GLMN... 168 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-36 1 gene 231 variants
PAX2 variant database PAX2 78 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-36 1 gene 211 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
http://149.142.212.78/LOVD/ LOVD 2.0-31 1 gene 190 variants
UCLA Neurogenetics SETX Database SETX 121 unique
https://lovd3.isciii.es/ LOVD 3.0-11 31 genes 188 variants
SpainMDB ABCD1,APC,ATP7B,BRAF,BRCA1,BRCA2,BSND... 137 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-36 4 genes 186 variants
LOVD - Leiden Open Variation Database CHM,PRPF8,RB1,RHO 73 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-36 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://dna2.leeds.ac.uk/LOVD/ LOVD 3.0-13 14 genes 180 variants
LOVD - Leiden Open Variation Database AMBN,AMELX,C4orf26,COL17A1,ENAM,FAM20... 120 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-36 1 gene 171 variants
LOVD - Leiden Open Variation Database PORCN 119 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-36 5 genes 140 variants
University of Heidelberg Serotonin receptor variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 63 unique
http://nndimontreal.ca/ LOVD 3.0-03 2 genes 133 variants
LOVD - Leiden Open Variation Database AQP2,AVPR2 8 unique
http://medgen.ua.ac.be/LOVDv.3.0/ LOVD 3.0-14 5 genes 115 variants
LOVD - Leiden Open Variation Database SMAD3,TGFB2,TGFB3,TGFBR1,TGFBR2 47 unique
http://database.LOVD.nl/shared/ LOVD 3.0-14 35 genes 114 variants
LOVD - Leiden Open Variation Database ANXA7,AR,BRCA1,BRCA2,CD82,CDH1,CDKN1B... 113 unique
http://server.goldenhelix.org/a1atvar/ LOVD 2.0-30 1 gene 94 variants
a1atvar SERPINA1 66 unique
http://sysbio.org.cn LOVD 2.0-33 1 gene 80 variants
Alexander disease_NDDMD GFAP 70 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-36 1 gene 50 variants
Cleft Lip and Palate Mutation Database IRF6 40 unique
http://databases.locd.nl/shared/ LOVD 3.0-13 3 genes 43 variants
National Thalassemia Database HBA1,HBA2,HBB 24 unique
http://ibio-cn.org LOVD 2.0-31 1 gene 30 variants
Canavan Disease_NDDMD ASPA 22 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-36 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://haemgen.haem.cam.ac.uk/lovd/ LOVD 3.0-09 2 genes 2 variants
LOVD - Leiden Open Variation Database FGA,ITGA2B 2 unique
http://www.medgen.mcgill.ca/nndi/ LOVD 2.0-16 1 gene 2 variants
nndi AVP 1 unique
http://lovd-nefro.unipoli.unimo.it/LOVDv.3.0/ LOVD 3.0-08 2 genes 1 variants
LOVD - Leiden Open Variation Database PKD1,PKD2 1 unique
http://www.medgen.mcgill.ca/ANO5/ LOVD 2.0-24 1 gene 1 variants
ANO5 LOVD - Leiden Open Variation Database ANO5 1 unique
http://genet.ir/variome/ LOVD 3.0-14 9063 genes 0 variants
Iran Variation Database A2M,A2ML1,A4GALT,AACS,AADACL2,AADAT,A... 0 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-36 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
https://atlas.cmm.ki.se/LOVDv.2.0/ LOVD 2.0-31 1 gene 0 variants
LOVD - Leiden Open Variation Database MLH1 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-36 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://hvpmalaysia.kk.usm.my LOVD 3.0-13 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://www.genosserver.com/LOVD/ LOVD 3.0-14 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://clinbiodb2015.univ-angers.fr/LOVDv.3.0/ LOVD 3.0-13 0 genes 0 variants
#clinbiodb2015 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-36 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://databases.lovd.nl/DNA_profiles/ LOVD 3.0-14 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://bchanglab.noip.me/ LOVD 2.0-35 0 genes 0 variants
Chang Lab LOVDatabase 0 unique
http://raredis-k.nibio.go.jp/LOVD/ LOVD 3.0-09 ? genes ? variants
LOVD - The Japan Society of Pediatric Genetics ? unique
(This list is updated daily and shows LOVD 2.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2015/08/06 11:57:09 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen