Information For all details about LOVD, see our LOVD flyer! (last updated June 6th, 2013)
By the way, did you already know LOVD 3.0 is out?

List of public LOVD installations

Question If you are looking for a specific gene database, please also check the list of gene variant databases at the HGVS site, or in our list of LSDBs.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 2,474,987 variants (2,170,923 unique) in 183,377 individuals in 88 LOVD installations.
http://databases.lovd.nl/whole_genome/ LOVD 3.0-09 22002 genes 1998175 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 1998135 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-35 157 genes 85096 variants
Leiden Muscular Dystrophy pages ACTA1,ACTC1,AGRN,ANKRD1,ANO5,ARHGEF10... 14235 unique
http://databases.lovd.nl/shared/ LOVD 3.0-09 22043 genes 71339 variants
LOVD 3.0 shared installation A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,... 16281 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-35 324 genes 50042 variants
Mendelian genes ABCC11,ABO,ACTB,ACTG1,ACVR1,ADA,ADAMT... 8532 unique
http://proteomics.bio21.unimelb.edu.au/lovd/ LOVD 3.0-07 14772 genes 45360 variants
LOVD - Leiden Open Variation Database A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A... 45067 unique
http://chromium.liacs.nl/LOVD2/colon_cancer/ LOVD 2.0-35 11 genes 29003 variants
Colon cancer gene variant databases APC,CDH1,EPCAM,GALNT12,MLH1,MLH3,MSH2... 4557 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-35 515 genes 28873 variants
X-chromosome gene database ABCB7,ABCD1,ACE2,ACOT9,ACSL4,ACTRT1,A... 4142 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 8 genes 26150 variants
LOVD - human mismatch repair genes MLH1,MLH1_priors,MSH2,MSH2_priors,MSH... 26150 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-35 16 genes 20566 variants
Retinal and hearing impairment genetic mutation database CDH23,CHM,CLRN1,GPR98,MYO15A,MYO7A,OT... 2845 unique
http://www.genomed.org/lovd2/ LOVD 2.0-35 96 genes 14899 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN... 9261 unique
http://chromium.liacs.nl/LOVD2/TSC/ LOVD 2.0-35 2 genes 10565 variants
Tuberous sclerosis database TSC1,TSC2 2466 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-35 3 genes 9688 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 641 unique
http://chromium.liacs.nl/LOVD2/ LOVD 2.0-35 38 genes 9500 variants
LOVD - Leiden Open Variation Database ABCA13,ADAR,ARG1,ASL,ASS1,ATM,ATP1A2,... 3452 unique
http://grenada.lumc.nl/LOVD2/eye/ LOVD 2.0-35 208 genes 9200 variants
Eye diseases - LOVD ABCA4,ABCB5,ABCC6,ABHD12,ACBD5,ADAM9,... 1792 unique
https://grenada.lumc.nl/LOVD2/shared1/ LOVD 2.0-35 129 genes 6324 variants
LOVD - Leiden Open Variation Database AARS,ACO2,ACP5,AGK,ALG11,ANKH,ARID1A,... 1530 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-35 4 genes 6048 variants
EAHAD Coagulation Factor Variant Databases F8,F9,GP1BA,VWF 1769 unique
https://research.cchmc.org/LOVD2/ LOVD 2.0-34 49 genes 4588 variants
**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database ABCB11,ABCB4,ACADM,ACADVL,ATP8B1,CASP... 4307 unique
https://mseqdr.org/MITO/ LOVD 3.0-09 1331 genes 3354 variants
MSeqDR-LSDB Mitochondrial Disease Locus Specific Database AADAT,AARS2,AASS,ABAT,ABCA9,ABCB10,AB... 2975 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3186 variants
rb1-lsdb RB1 1610 unique
http://grenada.lumc.nl/LOVD2/COL4A/ LOVD 2.0-35 4 genes 3036 variants
Collagen, type IV, alpha COL4A3,COL4A4,COL4A5,COL4A6 1711 unique
https://lovd.euro-wabb.org/ LOVD 2.0-30 23 genes 2886 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,ARL6,BBIP1,BBS1,BBS10,BBS12,BBS... 878 unique
http://chromium.liacs.nl/LOVD2/cancer/ LOVD 2.0-35 2 genes 2755 variants
LOVD - Leiden Open Variation Database BRCA1,BRCA2 1101 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-35 16 genes 2718 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FKBP... 1482 unique
http://chromium.liacs.nl/LOVD2/FANC/ LOVD 2.0-35 16 genes 2530 variants
Fanconi anemia database FANCA,FANCB,FANCC,FANCD1,FANCD2,FANCE... 827 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-35 7 genes 2317 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,... 431 unique
http://grenada.lumc.nl/LOVD2/PKD/ LOVD 2.0-35 2 genes 2187 variants
Autosomal Dominant Polycystic Kidney Disease (ADPKD) PKD1,PKD2 76 unique
http://lovd.bx.psu.edu/ LOVD 2.0-35 37 genes 2100 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CN... 2042 unique
http://www.ucl.ac.uk/ldlr/Current/ LOVD 1.1.0-12 3 genes 1943 variants
British Heart Foundation LDLR,LDLRAP1,PCSK9 1255 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1601 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,... 958 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-35 5 genes 1447 variants
LOVD - Leiden Open Variation Database NIPBL,PDS5A,PDS5B,SMC1A,SMC3 321 unique
http://secure.ngrl.org.uk/LOVDv.2.0/ LOVD 2.0-28 5 genes 1404 variants
NGRL, Manchester LOVD CHM,KDM6A,L1CAM,MLL2,UBE3A 540 unique
http://www.ncbi.nlm.nih.gov/lovd/ LOVD 2.0-35 5 genes 1148 variants
LOVD at NCBI ABCC6,DOCK8,FAS,IL2RG,OCRL 693 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-35 8 genes 1129 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 605 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-35 6 genes 1121 variants
Parkinson's disease Mutation Database LRRK2,PARK11,PARK2,PARK7,PINK1,SNCA 987 unique
http://medgen.ua.ac.be/LOVDv.2.0/ LOVD 2.0-33 2 genes 1102 variants
Multiple Osteochondroma Mutation Database EXT1,EXT2 657 unique
http://145.88.210.23/www.dbpex.org/ LOVD 2.0-30 13 genes 1079 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PE... 388 unique
http://chromium.liacs.nl/LOVD2/SDH/ LOVD 2.0-35 6 genes 1060 variants
TCA Cycle Gene Mutation Database FH,SDHA,SDHAF2,SDHB,SDHC,SDHD 579 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-35 10 genes 922 variants
Ehlers-Danlos Syndrome Variant Database ADAMTS2,B4GALT7,CHST14,COL3A1,COL5A1,... 629 unique
http://mitodyn.org/ LOVD 2.0-35 2 genes 735 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 363 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-35 1 gene 685 variants
HGD mutation database HGD 162 unique
http://ihg.helmholtz-muenchen.de/LOVDv.2.0/ LOVD 2.0-28 10 genes 582 variants
LOVD - Munich Open Variation Database ABCC8,DMP1,ENPP1,FGF23,KCNJ11,MC2R,MR... 211 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-35 1 gene 510 variants
Menkes Disease ATP7A 323 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-35 3 genes 500 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 143 unique
http://chromium.liacs.nl/LOVD2/growth/ LOVD 2.0-35 6 genes 491 variants
LOVD - Leiden Open Variation Database GHR,IGF1,IGF1R,IGF2,IGFALS,STAT5B 150 unique
http://www-huge.uni-regensburg.de/BEST1_database/ LOVD 2.0-23 1 gene 394 variants
Bestrophin 1 (BEST1) BEST1 269 unique
http://www.dbagenes.unito.it/ LOVD 2.0-25 13 genes 378 variants
Diamond-Blackfan Anemia GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,... 240 unique
https://grenada.lumc.nl/LOVD2/UCL-Heart/ LOVD 2.0-35 4 genes 363 variants
FH UCL BHF FTH1,HAMP,LDLR,TFR2 334 unique
http://rpgr.hgu.mrc.ac.uk/ LOVD 1.1.0-05 1 gene 358 variants
Retinitis Pigmentosa GTPase Regulator database RPGR 358 unique
http://genome.igib.res.in/tblovd/ LOVD 2.0-20 71 genes 341 variants
TBsLVD Tuberculosis susceptibility Locus Variation Database AKT1,ALOX5,BTNL2,CCL1,CCL2,CCL5,CD14,... 273 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-35 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-35 5 genes 330 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 278 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-35 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://sysbio.org.cn/ LOVD 2.0-33 35 genes 269 variants
PCaMDB : A mutation database for prostate cancer ANXA7,AR,BRCA1,BRCA2,CD82,CDH1,CDKN1B... 265 unique
http://www.icp.ucl.ac.be/vikkula/VAdb/ LOVD 2.0-35 16 genes 233 variants
Vascular Anomaly and Lymphedema Mutation Database CCBE1,CCM2,FLT4,FOXC2,GATA2,GJC2,GLMN... 154 unique
http://fishmap2.igib.res.in/mirlovd/ LOVD 2.0-35 157 genes 225 variants
miRvar MIR101_2,MIR10B,MIR1178,MIR1181,MIR11... 188 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-35 1 gene 211 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-35 1 gene 206 variants
PAX2 variant database PAX2 65 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-35 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://149.142.212.78/LOVD/ LOVD 2.0-31 1 gene 174 variants
UCLA Neurogenetics SETX Database SETX 107 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-35 1 gene 171 variants
LOVD - Leiden Open Variation Database PORCN 119 unique
http://nndimontreal.ca/ LOVD 3.0-03 2 genes 133 variants
LOVD - Leiden Open Variation Database AQP2,AVPR2 8 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-35 5 genes 118 variants
University of Heidelberg Serotonin receptor variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 59 unique
http://lovd.abcc.ncifcrf.gov/ LOVD 2.0-22 2 genes 115 variants
ABCC's LOVD - Leiden Open Variation Database FLCN,TGM1 83 unique
http://server.goldenhelix.org/a1atvar/ LOVD 2.0-30 1 gene 94 variants
a1atvar SERPINA1 66 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-35 1 gene 50 variants
Cleft Lip and Palate Mutation Database IRF6 40 unique
https://grenada.lumc.nl/LOVD2/BCM/ LOVD 2.0-35 1 gene 29 variants
Baylor College of Medicine KAT6B 23 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-35 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://hvpmalaysia.kk.usm.my/mhgvc/index.php?id=login LOVD 3.0-09 4 genes 6 variants
MyHVP - Human Variome Project Malaysia Database CFTR,G6PD,MSX1,RB1 5 unique
http://www.medgen.mcgill.ca/nndi/ LOVD 2.0-16 1 gene 2 variants
nndi AVP 1 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-35 1 gene 2 variants
LOVD - Leiden Open Variation Database PRPF8 2 unique
http://www.med.uni-magdeburg.de/lovd/ LOVD 2.0-26 1 gene 2 variants
Magdeburg Mutation Database LAMB2 1 unique
http://genome.igib.res.in/snolovd/ LOVD 2.0-35 124 genes 1 variants
snoLOVD SNORA11B,SNORA12,SNORA13,SNORA16B,SNO... 181 unique
http://medgen.ua.ac.be/LOVDv.3.0/ LOVD 3.0-09 4 genes 1 variants
LOVD - Leiden Open Variation Database SMAD3,TGFB2,TGFBR1,TGFBR2 1 unique
http://lovd-nefro.unipoli.unimo.it/LOVDv.3.0/ LOVD 3.0-08 2 genes 1 variants
LOVD - Leiden Open Variation Database PKD1,PKD2 1 unique
http://www.medgen.mcgill.ca/ANO5/ LOVD 2.0-24 1 gene 1 variants
ANO5 LOVD - Leiden Open Variation Database ANO5 1 unique
http://37.28.156.135/lovd/ LOVD 2.0-35 1 gene 1 variants
LOVD - Leiden Open Variation Database COL1A2 1 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-35 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
https://grenada.lumc.nl/LOVD2/vumc/CTD/ LOVD 2.0-35 4 genes 0 variants
Connective tissue disorders (VUMC Amsterdam) ACTA2,COL10A1,COL4A1,MYH11 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-35 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
https://atlas.cmm.ki.se/LOVDv.2.0/ LOVD 2.0-31 1 gene 0 variants
LOVD - Leiden Open Variation Database MLH1 0 unique
http://www.genomed.org/lovd2 LOVD 2.0-35 1 gene 0 variants
123 GJB6 0 unique
http://www.petasta.dc7.us LOVD 3.0-09 0 genes 0 variants
PeTasta 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-35 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://dnadb.info/ LOVD 2.0-31 0 genes 0 variants
International DNA Database 0 unique
http://CNDP1.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
CNDP1 MUI 0 unique
http://www.ibio-cn.org/NDDmutbase/ LOVD 2.0-35 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 ? genes ? variants
LOVD - IARC ? unique
http://raredis-k.nibio.go.jp/LOVD/ LOVD 3.0-09 ? genes ? variants
LOVD - The Japan Society of Pediatric Genetics ? unique
(This list is updated daily and shows LOVD 2.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2014/03/25 15:03:53 CET

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen