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LOVD v.2.0 - Leiden Open Variation DatabaseOnline gene-centered collection and display of DNA variants |
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LOVD Gene configuration areaCurating variantsAs a curator, your most important job is to keep the variants in your gene database(s) up to date and to curate new entries submitted to the system. New entries sent in by submitters are always hidden from the public view until you publish the entry. This also works the other way around, you can unpublish entries previously publicly available. Of each variant entry, you control whether it's visible to the public or not. The patient information will be hidden from the public if none of all associated variants are public.You will always have full access to the variants in your gene database and the connected patients, provided these patients aren't also connected to a gene you do not have access to. To edit those patients, you'll need at least a manager account. To curate entries one by one, use one of the two links that are displayed in the configuration area that point to the variant overviews; "View all uncurated entries in the ... gene database" shows all newly submitted, non-public and marked entries and the "View all entries in the ... gene database" link shows all entries, whether or not they are public. More about the different ways to view and search the variant listings in viewing and searching variant and patient data. From any of these two overviews, if you click on a variant entry, you will see a detailed overview of the patient and variant information, possibly including information about other variants found in the same patient. The detailed overview provides you links to curator tasks provided you have access; editing the patient information, quick-curating or editing the variant information, adding a new variant to the patient, deleting a variant or removing the whole submission (all patient and variant data) all in once. Also available from the configuration area is the "Curate all" option, that quick-curates all marked and non-public entries in the gene database. Only entries that are filled in completely will be published, other entries will be left.
When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63. |
